Mark Twain House was the home of Mark Twain (a.k.a. Samuel Langhorne Clemens) from 1871 to 1891 in Hartford, Connecticut, USA.

Prior to 1871, Twain lived in Hannibal, Missouri. The architectural style of the 19-room house itself is Victorian Gothic.

The house is also notable for the major works written during his residency, including The Gilded Age, The Adventures of Tom Sawyer, The Prince and the Pauper, Life on the Mississippi, Huckleberry Finn, A Tramp Abroad and A Connecticut Yankee in King Arthur's Court.

Bad financial investments caused the Twain family to move to Europe, and when they returned to Connecticut in 1900 he lived in a house built for him in Stormfield, Connecticut, where he died on April 21st, 1910. It has functioned as a school, an apartment building and a library, but since 1974 has been a National Historic Landmark, and undergone a multi-million dollar renovation and expansion dedicated to showcasing his life and work.